1c0e: Difference between revisions

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[[Image:1c0e.png|left|200px]]


{{STRUCTURE_1c0e|  PDB=1c0e  |  SCENE=  }}
==Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase==
 
<StructureSection load='1c0e' size='340' side='right'caption='[[1c0e]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1c0e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C0E FirstGlance]. <br>
{{ABSTRACT_PUBMED_10512620}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c0e OCA], [https://pdbe.org/1c0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c0e RCSB], [https://www.ebi.ac.uk/pdbsum/1c0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c0e ProSAT]</span></td></tr>
[[1c0e]] is a 2 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C0E OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PPAC_BOVIN PPAC_BOVIN] Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c0/1c0e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c0e ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]]
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
__TOC__
 
</StructureSection>
==Reference==
<ref group="xtra">PMID:010512620</ref><references group="xtra"/>
[[Category: Acid phosphatase]]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Etten, R L.Van.]]
[[Category: Large Structures]]
[[Category: Evans, B N.]]
[[Category: Evans BN]]
[[Category: Stauffacher, C V.]]
[[Category: Stauffacher CV]]
[[Category: Tabernero, L.]]
[[Category: Tabernero L]]
[[Category: Tishmack, P A.]]
[[Category: Tishmack PA]]
[[Category: Hydrolase]]
[[Category: Van Etten RL]]
[[Category: Phosphatase dimer]]
[[Category: Tyrosine phosphatase]]
Retrieved from "https://proteopedia.org/1c0e"