3de8: Difference between revisions

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[[Image:3de8.png|left|200px]]


{{STRUCTURE_3de8| PDB=3de8 | SCENE= }}
==Crystal Structure of a Dimeric Cytochrome cb562 Assembly Induced by Copper Coordination==
<StructureSection load='3de8' size='340' side='right'caption='[[3de8]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3de8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DE8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DE8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3de8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3de8 OCA], [https://pdbe.org/3de8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3de8 RCSB], [https://www.ebi.ac.uk/pdbsum/3de8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3de8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/3de8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3de8 ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We describe the metal-dependent self-assembly of symmetrical protein homooligomers from protein building blocks that feature appropriately engineered metal-chelating motifs on their surfaces. Crystallographic studies indicate that the same four-helix-bundle protein construct, MBPC-1, can self-assemble into C(2) and C(3) symmetrical assemblies dictated by Cu(II) and Ni(II) coordination, respectively. The symmetry inherent in metal coordination can thus be directly applied to biological self-assembly.


===Crystal Structure of a Dimeric Cytochrome cb562 Assembly Induced by Copper Coordination===
Control of protein oligomerization symmetry by metal coordination: C2 and C3 symmetrical assemblies through Cu(II) and Ni(II) coordination.,Salgado EN, Lewis RA, Mossin S, Rheingold AL, Tezcan FA Inorg Chem. 2009 Apr 6;48(7):2726-8. PMID:19267481<ref>PMID:19267481</ref>


{{ABSTRACT_PUBMED_19267481}}
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
</div>
==About this Structure==
<div class="pdbe-citations 3de8" style="background-color:#fffaf0;"></div>
[[3de8]] is a 4 chain structure of [[Cytochrome b5]] and [[Cytochrome c]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DE8 OCA].


==See Also==
==See Also==
*[[Cytochrome b5|Cytochrome b5]]
*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
*[[Cytochrome c|Cytochrome c]]
*[[Cytochrome b5 3D structures|Cytochrome b5 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:019267481</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Lewis, R A.]]
[[Category: Large Structures]]
[[Category: Rheingold, A L.]]
[[Category: Lewis RA]]
[[Category: Salgado, E N.]]
[[Category: Rheingold AL]]
[[Category: Tezcan, F A.]]
[[Category: Salgado EN]]
[[Category: Cu-stabilized dimeric superstructure]]
[[Category: Tezcan FA]]
[[Category: Electron transport]]
[[Category: Heme]]
[[Category: Iron]]
[[Category: Metal binding protein]]
[[Category: Metal-binding]]
[[Category: Transport]]