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[[Image:1a7w.png|left|200px]]


{{STRUCTURE_1a7w|  PDB=1a7w  |  SCENE=  }}
==CRYSTAL STRUCTURE OF THE HISTONE HMFB FROM METHANOTHERMUS FERVIDUS==
 
<StructureSection load='1a7w' size='340' side='right'caption='[[1a7w]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
===CRYSTAL STRUCTURE OF THE HISTONE HMFB FROM METHANOTHERMUS FERVIDUS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1a7w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermus_fervidus Methanothermus fervidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A7W FirstGlance]. <br>
{{ABSTRACT_PUBMED_11021968}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7w OCA], [https://pdbe.org/1a7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a7w RCSB], [https://www.ebi.ac.uk/pdbsum/1a7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a7w ProSAT]</span></td></tr>
[[1a7w]] is a 1 chain structure of [[Histone]] with sequence from [http://en.wikipedia.org/wiki/Methanothermus_fervidus Methanothermus fervidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7W OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/HMFB_METFE HMFB_METFE] Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/1a7w_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a7w ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Archaeal Histones|Archaeal Histones]]
*[[Histone 3D structures|Histone 3D structures]]
*[[Histone|Histone]]
__TOC__
 
</StructureSection>
==Reference==
[[Category: Large Structures]]
<ref group="xtra">PMID:011021968</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
[[Category: Methanothermus fervidus]]
[[Category: Methanothermus fervidus]]
[[Category: Decanniere, K.]]
[[Category: Decanniere K]]
[[Category: Heinemann, U.]]
[[Category: Heinemann U]]
[[Category: Reeve, J N.]]
[[Category: Reeve JN]]
[[Category: Sandman, K.]]
[[Category: Sandman K]]
[[Category: Histone]]

Latest revision as of 06:28, 7 February 2024

CRYSTAL STRUCTURE OF THE HISTONE HMFB FROM METHANOTHERMUS FERVIDUS

1a7w, resolution 1.55Å

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