3opy: Difference between revisions
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==Crystal structure of Pichia pastoris phosphofructokinase in the T-state== | |||
<StructureSection load='3opy' size='340' side='right'caption='[[3opy]], [[Resolution|resolution]] 3.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3opy]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Komagataella_pastoris_DSMZ_70382 Komagataella pastoris DSMZ 70382]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OPY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3opy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opy OCA], [https://pdbe.org/3opy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3opy RCSB], [https://www.ebi.ac.uk/pdbsum/3opy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3opy ProSAT]</span></td></tr> | ||
[[3opy]] is a 12 chain structure | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PFKA1_PICPA PFKA1_PICPA] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03184]<ref>PMID:12125050</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/3opy_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3opy ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Phosphofructokinase | *[[Phosphofructokinase 3D structures|Phosphofructokinase 3D structures]] | ||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Komagataella pastoris DSMZ 70382]] | ||
[[Category: Bruser | [[Category: Large Structures]] | ||
[[Category: Keim | [[Category: Bruser A]] | ||
[[Category: Kirchberger | [[Category: Keim A]] | ||
[[Category: Kloos | [[Category: Kirchberger J]] | ||
[[Category: Kuettner | [[Category: Kloos M]] | ||
[[Category: Marek | [[Category: Kuettner EB]] | ||
[[Category: Schoneberg | [[Category: Marek S]] | ||
[[Category: Strater | [[Category: Schoneberg T]] | ||
[[Category: Strater N]] | |||
Latest revision as of 10:35, 21 February 2024
Crystal structure of Pichia pastoris phosphofructokinase in the T-state
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