2wje: Difference between revisions

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[[Image:2wje.png|left|200px]]


{{STRUCTURE_2wje|  PDB=2wje  |  SCENE= }}
==Crystal structure of the tyrosine phosphatase Cps4B from Steptococcus pneumoniae TIGR4.==
 
<StructureSection load='2wje' size='340' side='right'caption='[[2wje]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE CPS4B FROM STEPTOCOCCUS PNEUMONIAE TIGR4.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2wje]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJE FirstGlance]. <br>
{{ABSTRACT_PUBMED_19616007}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.899&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wje OCA], [https://pdbe.org/2wje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wje RCSB], [https://www.ebi.ac.uk/pdbsum/2wje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wje ProSAT]</span></td></tr>
[[2wje]] is a 1 chain structure of [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJE OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/CPSB_STRPN CPSB_STRPN] Dephosphorylates CpsD. Involved in the regulation of capsular polysaccharide biosynthesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wje_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wje ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:019616007</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
[[Category: Hagelueken, G.]]
[[Category: Hagelueken G]]
[[Category: Huang, H.]]
[[Category: Huang H]]
[[Category: Naismith, J H.]]
[[Category: Naismith JH]]
[[Category: Capsule biogenesis/degradation]]
[[Category: Exopolysaccharide synthesis]]
[[Category: Hydrolase]]
[[Category: Manganese]]
[[Category: Phosphatase]]
[[Category: Protein phosphatase]]
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