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[[Image:1enz.png|left|200px]]


{{STRUCTURE_1enz|  PDB=1enz  |  SCENE=  }}
==CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS==
 
<StructureSection load='1enz' size='340' side='right'caption='[[1enz]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1enz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ENZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ENZ FirstGlance]. <br>
{{ABSTRACT_PUBMED_7886450}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1enz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1enz OCA], [https://pdbe.org/1enz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1enz RCSB], [https://www.ebi.ac.uk/pdbsum/1enz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1enz ProSAT], [https://www.topsan.org/Proteins/TBSGC/1enz TOPSAN]</span></td></tr>
[[1enz]] is a 1 chain structure of [[Enoyl-Acyl-Carrier Protein Reductase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ENZ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1enz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1enz ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:007886450</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Blanchard, J S.]]
[[Category: Blanchard JS]]
[[Category: Dessen, A.]]
[[Category: Dessen A]]
[[Category: Jacobs, W R.]]
[[Category: Jacobs Jr WR]]
[[Category: Quemard, A.]]
[[Category: Quemard A]]
[[Category: Sacchettini, J C.]]
[[Category: Sacchettini JC]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Oxidoreductase]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Tb structural genomics consortium]]
[[Category: Tbsgc]]
Retrieved from "https://proteopedia.org/1enz"