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[[Image:3ked.png|left|200px]]


{{STRUCTURE_3ked|  PDB=3ked  |  SCENE=  }}
==Crystal structure of Aminopeptidase N in complex with 2,4-diaminobutyric acid==
 
<StructureSection load='3ked' size='340' side='right'caption='[[3ked]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
===Crystal structure of Aminopeptidase N in complex with 2,4-diaminobutyric acid===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ked]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KED FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAB:2,4-DIAMINOBUTYRIC+ACID'>DAB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[3ked]] is a 1 chain structure of [[Aminopeptidase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KED OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ked FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ked OCA], [https://pdbe.org/3ked PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ked RCSB], [https://www.ebi.ac.uk/pdbsum/3ked PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ked ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.


==See Also==
==See Also==
*[[Aminopeptidase|Aminopeptidase]]
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022025387</ref><references group="xtra"/>
[[Category: Escherichia coli K-12]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Membrane alanyl aminopeptidase]]
[[Category: Addlagatta A]]
[[Category: Addlagatta, A.]]
[[Category: Gumpena R]]
[[Category: Gumpena, R.]]
[[Category: Amino switch]]
[[Category: Aminopeptidase]]
[[Category: Cell inner membrane]]
[[Category: Cell membrane]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Ligand design]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Metalloprotease]]
[[Category: Protease]]
[[Category: Thermolysin like active site]]

Latest revision as of 16:11, 1 November 2023

Crystal structure of Aminopeptidase N in complex with 2,4-diaminobutyric acid

3ked, resolution 2.30Å

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