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[[Image:3rim.png|left|200px]]


{{STRUCTURE_3rim|  PDB=3rim  |  SCENE=  }}
==Crystal structure of mycobacterium tuberculosis Transketolase (Rv1449c)==
 
<StructureSection load='3rim' size='340' side='right'caption='[[3rim]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
===Crystal structure of mycobacterium tuberculosis Transketolase (Rv1449c)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3rim]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RIM FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
[[3rim]] is a 4 chain structure of [[Transketolase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIM OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rim OCA], [https://pdbe.org/3rim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rim RCSB], [https://www.ebi.ac.uk/pdbsum/3rim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rim ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TKT_MYCTU TKT_MYCTU] Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate. Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.[REFERENCE:3]


==See Also==
==See Also==
*[[Transketolase|Transketolase]]
*[[Transketolase 3D structures|Transketolase 3D structures]]
[[Category: Mycobacterium tuberculosis]]
__TOC__
[[Category: Transketolase]]
</StructureSection>
[[Category: Cole, S T.]]
[[Category: Large Structures]]
[[Category: Fullam, E.]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Jones, T A.]]
[[Category: Cole ST]]
[[Category: Pojer, F.]]
[[Category: Fullam E]]
[[Category: Mycobacterium]]
[[Category: Jones TA]]
[[Category: Tpp]]
[[Category: Pojer F]]
[[Category: Transferase]]
[[Category: Transketolase]]

Latest revision as of 12:25, 14 March 2024

Crystal structure of mycobacterium tuberculosis Transketolase (Rv1449c)

3rim, resolution 2.49Å

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