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[[Image:2rtl.png|left|200px]]


{{STRUCTURE_2rtl|  PDB=2rtl  |  SCENE=  }}
==STREPTAVIDIN-2-IMINOBIOTIN-SULFATE COMPLEX, PH 2.50, SPACE GROUP I4122==
 
<StructureSection load='2rtl' size='340' side='right'caption='[[2rtl]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
===STREPTAVIDIN-2-IMINOBIOTIN-SULFATE COMPLEX, PH 2.50, SPACE GROUP I4122===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2rtl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RTL FirstGlance]. <br>
{{ABSTRACT_PUBMED_9405158}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMI:2-IMINOBIOTIN'>IMI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rtl OCA], [https://pdbe.org/2rtl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rtl RCSB], [https://www.ebi.ac.uk/pdbsum/2rtl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rtl ProSAT]</span></td></tr>
[[2rtl]] is a 1 chain structure of [[Avidin]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RTL OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rt/2rtl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rtl ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Avidin|Avidin]]
*[[Avidin 3D structures|Avidin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:009405158</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
[[Category: Katz, B A.]]
[[Category: Katz BA]]
[[Category: Apostreptavidin]]
[[Category: Biotin-binding protein]]
[[Category: Ph 2 50]]
[[Category: Streptavidin-2-iminobiotin-sulfate]]