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[[Image:2a21.png|left|200px]]


{{STRUCTURE_2a21|  PDB=2a21  |  SCENE=  }}
==Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+==
 
<StructureSection load='2a21' size='340' side='right'caption='[[2a21]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2a21]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A21 FirstGlance]. <br>
{{ABSTRACT_PUBMED_19228070}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a21 OCA], [https://pdbe.org/2a21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a21 RCSB], [https://www.ebi.ac.uk/pdbsum/2a21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a21 ProSAT]</span></td></tr>
[[2a21]] is a 2 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A21 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/KDSA_AQUAE KDSA_AQUAE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/2a21_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a21 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aldolase|Aldolase]]
*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:019228070</ref><references group="xtra"/>
[[Category: 3-deoxy-8-phosphooctulonate synthase]]
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Gatti, D L.]]
[[Category: Large Structures]]
[[Category: Kona, F.]]
[[Category: Gatti DL]]
[[Category: Lu, J.]]
[[Category: Kona F]]
[[Category: Martin, P.]]
[[Category: Lu J]]
[[Category: Xu, X.]]
[[Category: Martin P]]
[[Category: Transferase]]
[[Category: Xu X]]
Retrieved from "https://proteopedia.org/2a21"