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[[Image:1evl.png|left|200px]]


{{STRUCTURE_1evl|  PDB=1evl  |  SCENE=  }}
==CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THREONYL-TRNA SYNTHETASE WITH A THREONYL ADENYLATE ANALOG==
 
<StructureSection load='1evl' size='340' side='right'caption='[[1evl]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
===CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THREONYL-TRNA SYNTHETASE WITH A THREONYL ADENYLATE ANALOG===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1evl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EVL FirstGlance]. <br>
{{ABSTRACT_PUBMED_10881191}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TSB:5-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE'>TSB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1evl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evl OCA], [https://pdbe.org/1evl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1evl RCSB], [https://www.ebi.ac.uk/pdbsum/1evl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1evl ProSAT]</span></td></tr>
[[1evl]] is a 4 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVL OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYT_ECOLI SYT_ECOLI] ThrS is also a translational repressor protein, it controls the translation of its own gene by binding to its mRNA.[HAMAP-Rule:MF_00184]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/1evl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1evl ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010881191</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Threonine--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Dock-Bregeon, A C.]]
[[Category: Dock-Bregeon AC]]
[[Category: Moras, D.]]
[[Category: Moras D]]
[[Category: Rees, B.]]
[[Category: Rees B]]
[[Category: Sankaranarayanan, R.]]
[[Category: Sankaranarayanan R]]
[[Category: Adenylate analog]]
[[Category: Amino acid recognition]]
[[Category: Deletion mutant]]
[[Category: Ligase]]
[[Category: Trna-synthetase]]
[[Category: Zinc ion]]
Retrieved from "https://proteopedia.org/1evl"