3ae2: Difference between revisions

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[[Image:3ae2.png|left|200px]]


{{STRUCTURE_3ae2|  PDB=3ae2  |  SCENE=  }}
==Crystal structure of porcine heart mitochondrial complex II bound with 2-Hydroxy-N-phenyl-benzamide==
 
<StructureSection load='3ae2' size='340' side='right'caption='[[3ae2]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
===Crystal structure of porcine heart mitochondrial complex II bound with 2-Hydroxy-N-phenyl-benzamide===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ae2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AE2 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SLI:2-HYDROXY-N-PHENYLBENZAMIDE'>SLI</scene></td></tr>
[[3ae2]] is a 4 chain structure of [[Succinate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AE2 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ae2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ae2 OCA], [https://pdbe.org/3ae2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ae2 RCSB], [https://www.ebi.ac.uk/pdbsum/3ae2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ae2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDHA_PIG SDHA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity).


==See Also==
==See Also==
*[[Succinate Dehydrogenase|Succinate Dehydrogenase]]
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Harada, S.]]
[[Category: Harada S]]
[[Category: Honma, T.]]
[[Category: Honma T]]
[[Category: Inaoka, D K.]]
[[Category: Inaoka DK]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kido, Y.]]
[[Category: Kido Y]]
[[Category: Kita, K.]]
[[Category: Kita K]]
[[Category: Mao, J.]]
[[Category: Mao J]]
[[Category: Matsuoka, S.]]
[[Category: Matsuoka S]]
[[Category: Omori, J.]]
[[Category: Omori J]]
[[Category: Osanai, A.]]
[[Category: Osanai A]]
[[Category: Sakamoto, K.]]
[[Category: Sakamoto K]]
[[Category: Sasaki, T.]]
[[Category: Sasaki T]]
[[Category: Shindo, M.]]
[[Category: Shindo M]]
[[Category: Tanaka, A.]]
[[Category: Tanaka A]]
[[Category: Electron transport]]
[[Category: Fad-binding protein]]
[[Category: Heme]]
[[Category: Inhibitor]]
[[Category: Iron]]
[[Category: Iron-sulfur]]
[[Category: Metal-binding]]
[[Category: Mitochondrion]]
[[Category: Mitochondrion inner membrane]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Respiratory complex ii]]
[[Category: Transit peptide]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Tricarboxylic acid cycle]]
Retrieved from "https://proteopedia.org/3ae2"