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[[Image:2gvw.png|left|200px]]


{{STRUCTURE_2gvw|  PDB=2gvw  |  SCENE=  }}
==Structure of diisopropyl fluorophosphatase (DFPase) holoenzyme (RT)==
 
<StructureSection load='2gvw' size='340' side='right'caption='[[2gvw]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
===Structure of diisopropyl fluorophosphatase (DFPase) holoenzyme (RT)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2gvw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GVW FirstGlance]. <br>
{{ABSTRACT_PUBMED_17002369}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvw OCA], [https://pdbe.org/2gvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gvw RCSB], [https://www.ebi.ac.uk/pdbsum/2gvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvw ProSAT]</span></td></tr>
[[2gvw]] is a 1 chain structure of [[Phosphotriesterase]] with sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVW OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DFPA_LOLVU DFPA_LOLVU] Biological function and substrate unknown. However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).<ref>PMID:15966726</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gvw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gvw ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphotriesterase|Phosphotriesterase]]
*[[Phosphotriesterase 3D structures|Phosphotriesterase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:017002369</ref><references group="xtra"/>
__TOC__
[[Category: Diisopropyl-fluorophosphatase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Loligo vulgaris]]
[[Category: Loligo vulgaris]]
[[Category: Blum, M M.]]
[[Category: Blum MM]]
[[Category: Chen, J C.H.]]
[[Category: Chen JCH]]
[[Category: Beta-propeller]]
[[Category: Hydrolase]]
[[Category: Phosphotriesterase]]
Retrieved from "https://proteopedia.org/2gvw"