1t00: Difference between revisions

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[[Image:1t00.png|left|200px]]


{{STRUCTURE_1t00|  PDB=1t00  |  SCENE=  }}
==The structure of thioredoxin from S. coelicolor==
 
<StructureSection load='1t00' size='340' side='right'caption='[[1t00]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
===The structure of thioredoxin from S. coelicolor===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1t00]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T00 FirstGlance]. <br>
{{ABSTRACT_PUBMED_16510983}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t00 OCA], [https://pdbe.org/1t00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t00 RCSB], [https://www.ebi.ac.uk/pdbsum/1t00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t00 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1t00]] is a 1 chain structure of [[Thioredoxin]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T00 OCA].  
== Function ==
[https://www.uniprot.org/uniprot/THIO1_STRCO THIO1_STRCO] Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Stimulates complex formation between sigma factor SigR and its cognate anti-sigma factor RsrA probably by reducing RsrA.<ref>PMID:10428967</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t0/1t00_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t00 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Thioredoxin|Thioredoxin]]
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:016510983</ref><references group="xtra"/>
__TOC__
[[Category: Streptomyces coelicolor]]
</StructureSection>
[[Category: Stefankova, P.]]
[[Category: Large Structures]]
[[Category: Electron transport]]
[[Category: Stefankova P]]
[[Category: Multifunction macromolecule]]
[[Category: Redox regulation]]
[[Category: S. coelicolor]]
[[Category: Thioredoxin]]

Latest revision as of 08:35, 14 February 2024

The structure of thioredoxin from S. coelicolor

1t00, resolution 1.51Å

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