1xo7: Difference between revisions

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[[Image:1xo7.png|left|200px]]


{{STRUCTURE_1xo7|  PDB=1xo7  |  SCENE=  }}
==Crystal structure of cyclophilin from Trypanosoma cruzi==
 
<StructureSection load='1xo7' size='340' side='right'caption='[[1xo7]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
===Crystal structure of cyclophilin from Trypanosoma cruzi===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1xo7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XO7 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xo7 OCA], [https://pdbe.org/1xo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xo7 RCSB], [https://www.ebi.ac.uk/pdbsum/1xo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xo7 ProSAT]</span></td></tr>
[[1xo7]] is a 4 chain structure of [[Cyclophilin]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XO7 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4DPB9_TRYCC Q4DPB9_TRYCC] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xo/1xo7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xo7 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cyclophilin|Cyclophilin]]
*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
[[Category: Caruthers, J M.]]
[[Category: Caruthers JM]]
[[Category: Hol, W G.J.]]
[[Category: Hol WGJ]]
[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
[[Category: Cis-tran]]
[[Category: Cruzi]]
[[Category: Cyclophilin]]
[[Category: Isomerase]]
[[Category: Proline]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Rotamase]]
[[Category: Sgpp]]
[[Category: Structural genomic]]
[[Category: Structural genomics of pathogenic protozoa consortium]]
[[Category: Trypanosoma]]

Latest revision as of 06:48, 23 August 2023

Crystal structure of cyclophilin from Trypanosoma cruzi

1xo7, resolution 1.61Å

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