1i6i: Difference between revisions

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[[Image:1i6i.png|left|200px]]


{{STRUCTURE_1i6i|  PDB=1i6i  |  SCENE=  }}
==CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP==
 
<StructureSection load='1i6i' size='340' side='right'caption='[[1i6i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1i6i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I6I FirstGlance]. <br>
{{ABSTRACT_PUBMED_11373668}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i6i OCA], [https://pdbe.org/1i6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i6i RCSB], [https://www.ebi.ac.uk/pdbsum/1i6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i6i ProSAT]</span></td></tr>
[[1i6i]] is a 1 chain structure of [[Kinesin]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6I OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/KIF1A_MOUSE KIF1A_MOUSE] Motor for anterograde axonal transport of synaptic vesicle precursors.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/1i6i_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i6i ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Kinesin|Kinesin]]
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:011373668</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Fletterick, R J.]]
[[Category: Fletterick RJ]]
[[Category: Hirokawa, N.]]
[[Category: Hirokawa N]]
[[Category: Kikkawa, M.]]
[[Category: Kikkawa M]]
[[Category: Okada, Y.]]
[[Category: Okada Y]]
[[Category: Sablin, E P.]]
[[Category: Sablin EP]]
[[Category: Yajima, H.]]
[[Category: Yajima H]]
[[Category: Catalytic core]]
[[Category: Kinesin]]
[[Category: Motor protein]]
[[Category: Transport protein]]

Latest revision as of 07:32, 7 February 2024

CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP

1i6i, resolution 2.00Å

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