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[[Image:1if2.png|left|200px]]


{{STRUCTURE_1if2|  PDB=1if2  |  SCENE=  }}
==X-RAY STRUCTURE OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH IPP==
 
<StructureSection load='1if2' size='340' side='right'caption='[[1if2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===X-RAY STRUCTURE OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH IPP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1if2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IF2 FirstGlance]. <br>
{{ABSTRACT_PUBMED_11589711}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=129:[2(FORMYL-HYDROXY-AMINO)-ETHYL]-PHOSPHONIC+ACID'>129</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1if2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1if2 OCA], [https://pdbe.org/1if2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1if2 RCSB], [https://www.ebi.ac.uk/pdbsum/1if2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1if2 ProSAT]</span></td></tr>
[[1if2]] is a 1 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IF2 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPIS_LEIME TPIS_LEIME]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/1if2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1if2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[TIM test|TIM test]]
*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
__TOC__
 
</StructureSection>
==Reference==
[[Category: Large Structures]]
<ref group="xtra">PMID:011589711</ref><references group="xtra"/>
[[Category: Leishmania mexicana]]
[[Category: Leishmania mexicana]]
[[Category: Triose-phosphate isomerase]]
[[Category: Antonov DM]]
[[Category: Antonov, D M.]]
[[Category: Augustyns K]]
[[Category: Augustyns, K.]]
[[Category: Kursula I]]
[[Category: Kursula, I.]]
[[Category: Lambeir A-M]]
[[Category: Lambeir, A M.]]
[[Category: Partanen S]]
[[Category: Partanen, S.]]
[[Category: Wierenga RK]]
[[Category: Wierenga, R K.]]
[[Category: Isomerase]]
[[Category: Tim barrel]]
[[Category: Transition state analogue]]
Retrieved from "https://proteopedia.org/1if2"