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[[Image:1j4a.png|left|200px]]


{{STRUCTURE_1j4a|  PDB=1j4a  |  SCENE=  }}
==INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS==
 
<StructureSection load='1j4a' size='340' side='right'caption='[[1j4a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1j4a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactobacillus_delbrueckii_subsp._bulgaricus Lactobacillus delbrueckii subsp. bulgaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J4A FirstGlance]. <br>
{{ABSTRACT_PUBMED_12054772}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j4a OCA], [https://pdbe.org/1j4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j4a RCSB], [https://www.ebi.ac.uk/pdbsum/1j4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j4a ProSAT]</span></td></tr>
[[1j4a]] is a 4 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_delbrueckii_subsp._bulgaricus Lactobacillus delbrueckii subsp. bulgaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4A OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDHD_LACDA LDHD_LACDA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/1j4a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j4a ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:012054772</ref><references group="xtra"/>
[[Category: D-lactate dehydrogenase]]
[[Category: Lactobacillus delbrueckii subsp. bulgaricus]]
[[Category: Lactobacillus delbrueckii subsp. bulgaricus]]
[[Category: Dauter, M.]]
[[Category: Large Structures]]
[[Category: Hottinger, H.]]
[[Category: Dauter M]]
[[Category: Kochhar, S.]]
[[Category: Hottinger H]]
[[Category: Lamzin, V S.]]
[[Category: Kochhar S]]
[[Category: Razeto, A.]]
[[Category: Lamzin VS]]
[[Category: Wilson, K S.]]
[[Category: Razeto A]]
[[Category: Nad-dependent dehydrogenase]]
[[Category: Wilson KS]]
[[Category: Oxidoreductase]]
[[Category: Reversible interconversion of pyruvate into d-lactate]]
Retrieved from "https://proteopedia.org/1j4a"