4g8z: Difference between revisions

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New page: '''Unreleased structure''' The entry 4g8z is ON HOLD Authors: Cody, Vivian Description: pcDHFR K37S/F69N double mutant TMP NADPH ternary complex
 
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'''Unreleased structure'''


The entry 4g8z is ON HOLD
==pcDHFR K37S/F69N double mutant TMP NADPH ternary complex==
<StructureSection load='4g8z' size='340' side='right'caption='[[4g8z]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4g8z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pneumocystis_jirovecii Pneumocystis jirovecii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G8Z FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TOP:TRIMETHOPRIM'>TOP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g8z OCA], [https://pdbe.org/4g8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g8z RCSB], [https://www.ebi.ac.uk/pdbsum/4g8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g8z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYR_PNECA DYR_PNECA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


Authors: Cody, Vivian
==See Also==
 
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
Description: pcDHFR K37S/F69N double mutant TMP NADPH ternary complex
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pneumocystis jirovecii]]
[[Category: Cody V]]
Retrieved from "https://proteopedia.org/4g8z"