4g9i: Difference between revisions
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The | ==Crystal structure of T.kodakarensis HypF== | ||
<StructureSection load='4g9i' size='340' side='right'caption='[[4g9i]], [[Resolution|resolution]] 4.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4g9i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G9I FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g9i OCA], [https://pdbe.org/4g9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g9i RCSB], [https://www.ebi.ac.uk/pdbsum/4g9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g9i ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q5JII4_THEKO Q5JII4_THEKO] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
HypF is involved in the biosynthesis of the CN ligand of the NiFe(CN)(2)CO centre of [NiFe]-hydrogenases. Here, the full-length structure of HypF from Thermococcus kodakarenesis is reported at 4.5 A resolution. The N-terminal acylphosphatase-like (ACP) domain interacts with the zinc-finger domain with some flexibility in its relative position. Molecular-surface analysis shows that a deep pocket formed between the ACP and zinc-finger domains is highly conserved and has positive potential. These results suggest that the positively charged pocket identified is involved in the hydrolysis of carbamoyl phosphate and the formation of a carbamoyl intermediate. | |||
Structure of the [NiFe]-hydrogenase maturation protein HypF from Thermococcus kodakarensis KOD1.,Tominaga T, Watanabe S, Matsumi R, Atomi H, Imanaka T, Miki K Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1153-7., doi: 10.1107/S1744309112036421. Epub 2012 Sep 22. PMID:23027738<ref>PMID:23027738</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 4g9i" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[HypA%2C HypB%2C HypC%2C HypD%2C HypE and HypF 3D structures|HypA%2C HypB%2C HypC%2C HypD%2C HypE and HypF 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermococcus kodakarensis KOD1]] | |||
[[Category: Atomi H]] | |||
[[Category: Imanaka T]] | |||
[[Category: Matsumi R]] | |||
[[Category: Miki K]] | |||
[[Category: Tominaga T]] | |||
[[Category: Watanabe S]] | |||
