4ag2: Difference between revisions

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[[Image:4ag2.png|left|200px]]


{{STRUCTURE_4ag2|  PDB=4ag2  |  SCENE=  }}
==Human Chymase - Fynomer Complex==
 
<StructureSection load='4ag2' size='340' side='right'caption='[[4ag2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Human Chymase - Fynomer Complex===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4ag2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AG2 FirstGlance]. <br>
{{ABSTRACT_PUBMED_22653218}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ag2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ag2 OCA], [https://pdbe.org/4ag2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ag2 RCSB], [https://www.ebi.ac.uk/pdbsum/4ag2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ag2 ProSAT]</span></td></tr>
[[4ag2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AG2 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
<ref group="xtra">PMID:022653218</ref><references group="xtra"/>
__TOC__
[[Category: Chymase]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Synthetic construct]]
[[Category: Banner, D W.]]
[[Category: Banner DW]]
[[Category: Batey, S.]]
[[Category: Batey S]]
[[Category: Benz, J.]]
[[Category: Benz J]]
[[Category: Bertschinger, J.]]
[[Category: Bertschinger J]]
[[Category: Brack, S.]]
[[Category: Brack S]]
[[Category: Grabulovski, D.]]
[[Category: Grabulovski D]]
[[Category: Hennig, M.]]
[[Category: Hennig M]]
[[Category: Huber, W.]]
[[Category: Huber W]]
[[Category: Joseph, C.]]
[[Category: Joseph C]]
[[Category: Kloosters, A Van Der.]]
[[Category: Rufer A]]
[[Category: Rufer, A.]]
[[Category: Schlatter D]]
[[Category: Schlatter, D.]]
[[Category: Van Der Kloosters A]]
[[Category: Weber, M.]]
[[Category: Weber M]]
[[Category: Hydrolase-de novo protein complex]]
[[Category: Inhibitor]]
[[Category: Serine protease]]
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