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[[Image:1ix9.jpg|left|200px]]<br /><applet load="1ix9" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1ix9, resolution 0.90&Aring;" />
'''Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution.'''<br />


==About this Structure==
==Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution.==
1IX9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MN:'>MN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX9 OCA].  
<StructureSection load='1ix9' size='340' side='right'caption='[[1ix9]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ix9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IX9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ix9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix9 OCA], [https://pdbe.org/1ix9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ix9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ix9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ix9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ix9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ix9 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Superoxide dismutase]]
[[Category: Anderson BF]]
[[Category: Anderson, B F.]]
[[Category: Baker EN]]
[[Category: Baker, E N.]]
[[Category: Edwards RA]]
[[Category: Edwards, R A.]]
[[Category: Jameson GB]]
[[Category: Jameson, G B.]]
[[Category: Whittaker JW]]
[[Category: Whittaker, J W.]]
[[Category: Whittaker MM]]
[[Category: Whittaker, M M.]]
[[Category: MN]]
[[Category: hydrogen bond]]
[[Category: manganese superoxide dismutase]]
[[Category: reactivity]]
[[Category: ultra-high resolution]]
[[Category: y174f mutant]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:16:38 2008''

Latest revision as of 07:12, 25 October 2023

Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution.

1ix9, resolution 0.90Å

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