4er8: Difference between revisions

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[[Image:4er8.jpg|left|200px]]


{{STRUCTURE_4er8|  PDB=4er8  |  SCENE=  }}
==Structure of the REP associates tyrosine transposase bound to a REP hairpin==
 
<StructureSection load='4er8' size='340' side='right'caption='[[4er8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
===Structure of the REP associates tyrosine transposase bound to a REP hairpin===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4er8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ER8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ER8 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
[[4er8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ER8 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4er8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4er8 OCA], [https://pdbe.org/4er8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4er8 RCSB], [https://www.ebi.ac.uk/pdbsum/4er8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4er8 ProSAT]</span></td></tr>
[[Category: Escherichia coli]]
</table>
[[Category: Chandler, M.]]
== Function ==
[[Category: Dyda, F.]]
[https://www.uniprot.org/uniprot/RAYT_ECOLI RAYT_ECOLI] Transposase that is always flanked by repeated extragenic palindrome (REP) sequences, which are clustered in structures called bacterial interspersed mosaic elements (BIMEs). RayT catalyzes cleavage and recombination of BIMEs. Binds REP sequences and cleaves BIMEs both upstream and downstream of the REP sequence. Could be important in the creation of BIME variability and amplification.<ref>PMID:20085626</ref> <ref>PMID:22199259</ref> <ref>PMID:22885300</ref>
[[Category: Ghirlando, R.]]
== References ==
[[Category: Hickman, A B.]]
<references/>
[[Category: Messing, S A.J.]]
__TOC__
[[Category: Ton-Hoang, B.]]
</StructureSection>
[[Category: Catalytic tyrosine]]
[[Category: Escherichia coli K-12]]
[[Category: Dna binding protein-dna complex]]
[[Category: Large Structures]]
[[Category: Guide sequence]]
[[Category: Chandler M]]
[[Category: Huh motif]]
[[Category: Dyda F]]
[[Category: Protein-dna complex]]
[[Category: Ghirlando R]]
[[Category: Rna recognition motif]]
[[Category: Hickman AB]]
[[Category: Transposase]]
[[Category: Messing SAJ]]
[[Category: Ton-Hoang B]]
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