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[[Image:4gcn.jpg|left|200px]]


{{STRUCTURE_4gcn|  PDB=4gcn  |  SCENE=  }}
==N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans==
 
<StructureSection load='4gcn' size='340' side='right'caption='[[4gcn]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
===N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4gcn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCN FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
[[4gcn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCN OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcn OCA], [https://pdbe.org/4gcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gcn RCSB], [https://www.ebi.ac.uk/pdbsum/4gcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/STIP1_CAEEL STIP1_CAEEL] Plays a role in gonad development. Up-regulates longevity and thermotolerance. Binds daf-21/hsp90 and inhibits its ATPase activity.<ref>PMID:19467242</ref> <ref>PMID:19559711</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Bigelow, L.]]
[[Category: Large Structures]]
[[Category: Gu, M.]]
[[Category: Bigelow L]]
[[Category: Joachimiak, A.]]
[[Category: Gu M]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Joachimiak A]]
[[Category: Morimoto, R I.]]
[[Category: Morimoto RI]]
[[Category: Oosten-Hawle, P Van.]]
[[Category: Osipiuk J]]
[[Category: Osipiuk, J.]]
[[Category: Van Oosten-Hawle P]]
[[Category: Co-chaperone]]
[[Category: Hop]]
[[Category: Hsp70]]
[[Category: Hsp70/hsp90-organising protein]]
[[Category: Hsp90]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Protein binding]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
[[Category: Tetratricopeptide repeat domain]]
[[Category: Tpr domain]]

Latest revision as of 11:27, 1 March 2024

N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans

4gcn, resolution 1.85Å

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