4g2l: Difference between revisions

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'''Unreleased structure'''


The entry 4g2l is ON HOLD  until Paper Publication
==Human PDE9 in complex with selective compound==
<StructureSection load='4g2l' size='340' side='right'caption='[[4g2l]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4g2l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G2L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0WL:1-CYCLOPENTYL-6-{(1R)-1-[3-(PYRIMIDIN-2-YL)AZETIDIN-1-YL]ETHYL}-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE'>0WL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g2l OCA], [https://pdbe.org/4g2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g2l RCSB], [https://www.ebi.ac.uk/pdbsum/4g2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g2l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDE9A_HUMAN PDE9A_HUMAN] Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.<ref>PMID:18757755</ref>


Authors: Liu, S.
==See Also==
 
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
Description: Human PDE9 in complex with selective compound
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Liu S]]
Retrieved from "https://proteopedia.org/4g2l"