4b8w: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 4b8w is ON HOLD Authors: Vollmar, M., Krojer, T., Shafqat, N., Rojkova, A., Bunkoczi, G., Pike, A., Chaikuat, A., Carpenter, E., Yue, W.W., Kavanagh... |
No edit summary |
||
| (8 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form== | |||
<StructureSection load='4b8w' size='340' side='right'caption='[[4b8w]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4b8w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B8W FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8w OCA], [https://pdbe.org/4b8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b8w RCSB], [https://www.ebi.ac.uk/pdbsum/4b8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b8w ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FCL_HUMAN FCL_HUMAN] Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bountra C]] | |||
[[Category: Bunkoczi G]] | |||
[[Category: Carpenter E]] | |||
[[Category: Chaikuat A]] | |||
[[Category: Edwards A]] | |||
[[Category: Kavanagh K]] | |||
[[Category: Krojer T]] | |||
[[Category: Oppermann U]] | |||
[[Category: Pike A]] | |||
[[Category: Rojkova A]] | |||
[[Category: Shafqat N]] | |||
[[Category: Vollmar M]] | |||
[[Category: Weigelt J]] | |||
[[Category: Yue WW]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 11:45, 20 December 2023
Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form
| ||||||||||||
