4gtf: Difference between revisions
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==T. Maritima FDTS (H53A mutant) with FAD, dUMP and Folate== | |||
<StructureSection load='4gtf' size='340' side='right'caption='[[4gtf]], [[Resolution|resolution]] 1.77Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4gtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GTF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MEF:N-({4-[(6AR)-3-AMINO-1-OXO-1,2,5,6,6A,7-HEXAHYDROIMIDAZO[1,5-F]PTERIDIN-8(9H)-YL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>MEF</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gtf OCA], [https://pdbe.org/4gtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gtf RCSB], [https://www.ebi.ac.uk/pdbsum/4gtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gtf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate. | |||
==See Also== | |||
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermotoga maritima MSB8]] | |||
[[Category: Kohen A]] | |||
[[Category: Lesley SA]] | |||
[[Category: Mathews II]] | |||
Latest revision as of 15:56, 14 March 2024
T. Maritima FDTS (H53A mutant) with FAD, dUMP and Folate
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