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[[Image:3sse.png|left|200px]]


{{STRUCTURE_3sse|  PDB=3sse  |  SCENE=  }}
==DNA binding domain of restriction endonuclease bound to DNA==
 
<StructureSection load='3sse' size='340' side='right'caption='[[3sse]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===DNA binding domain of restriction endonuclease bound to DNA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3sse]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSE FirstGlance]. <br>
{{ABSTRACT_PUBMED_22570415}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sse OCA], [https://pdbe.org/3sse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sse RCSB], [https://www.ebi.ac.uk/pdbsum/3sse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sse ProSAT]</span></td></tr>
==About this Structure==
</table>
[[3sse]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSE OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/MCRB_ECOLI MCRB_ECOLI] Recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines) produced by a broad range of DNA methylases and appears to act against 5-methylcytosine preceded by a purine residue. Binds to DNA containing methylated cytosines; also binds to GTP. Isoform 33 kDa is less active than isoform 51 kDa and may play a role in regulating the activity of isoform 51 kDa by competing with it in DNA and protein binding abilities.
==Reference==
__TOC__
<ref group="xtra">PMID:022570415</ref><references group="xtra"/>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli K-12]]
[[Category: Grazulis, S.]]
[[Category: Large Structures]]
[[Category: Siksnys, V.]]
[[Category: Grazulis S]]
[[Category: Sukackaite, R.]]
[[Category: Siksnys V]]
[[Category: Base flipping]]
[[Category: Sukackaite R]]
[[Category: Dna binding protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Restriction endonuclease]]

Latest revision as of 09:56, 1 March 2024

DNA binding domain of restriction endonuclease bound to DNA

3sse, resolution 2.70Å

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