EibD: Difference between revisions
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== Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD == | == Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD == | ||
<StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene=''> | <StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene='EibD/2xqh/1'> | ||
<!-- The line below this paragraph, {{ABSTRACT_PUBMED_21742268}}, adds the Publication Abstract to the page(as it appears on PubMed at http://www.pubmed.gov), where 21742268 is the PubMed ID number. --> | <!-- The line below this paragraph, {{ABSTRACT_PUBMED_21742268}}, adds the Publication Abstract to the page(as it appears on PubMed at http://www.pubmed.gov), where 21742268 is the PubMed ID number. --> | ||
{{ABSTRACT_PUBMED_21742268}} | {{ABSTRACT_PUBMED_21742268}} | ||
== | == Structure Features == | ||
Space Group: H 3 (48.950x48.950x409.600, 90.00x90.00x120.00) <br> | |||
Resolution limit: 1.99 Å <br> | |||
R/R free: 0.1585/0.1855 <br> | |||
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQH OCA].<br> | |||
<scene name='EibD/2xqh/1'>Asymmetric unit</scene> contains a single polypeptide chain. The <scene name='EibD/2xqh_ba/3'>biological assembly</scene> consists of three copies of the monomer related by a <scene name='EibD/2xqh_ba/11'>three fold axis</scene>. | |||
There are five distinct domains: | |||
<ul> | |||
<li>YadA-like <scene name='EibD/2xqh_ba/5'> β-roll</scene> domain; | |||
<li><scene name='EibD/2xqh_ba/6'>neck</scene> domain; | |||
<li><scene name='EibD/2xqh_ba/7'>right handed</scene> coiled-coil domain; | |||
<li><scene name='EibD/2xqh_ba/8'>mini β-sheet</scene> domain; | |||
<li><scene name='EibD/2xqh_ba/9'>left handed</scene> coiled-coil domain; | |||
</ul> | |||
Coiled-coil features: | |||
<ul> | |||
<li> cavities | |||
<li> chloride coordination by <scene name='EibD/2xqh_ba/12'>Thr</scene> and <scene name='EibD/2xqh_ba/13'>Asn</scene> residues. | |||
</ul> | |||
== General information == | == General information == | ||
Antibodies [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9 | Antibodies: [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9 RCSB PDB Molecule of the Month by David Goodsell] <ref>September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9</ref> | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 10:02, 9 January 2020
Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD
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Primery reference
- Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A. The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins. Structure. 2011 Jul 13;19(7):1021-30. PMID:21742268 doi:10.1016/j.str.2011.03.021
