2lw9: Difference between revisions

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[[Image:2lw9.jpg|left|200px]]


{{STRUCTURE_2lw9| PDB=2lw9 |  SCENE= }}
==NMR solution structure of Myo10 anti-CC==
<StructureSection load='2lw9' size='340' side='right'caption='[[2lw9]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2lw9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw9 OCA], [https://pdbe.org/2lw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw9 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYO10_HUMAN MYO10_HUMAN] Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podosome belt in osteoclasts (By similarity).<ref>PMID:16894163</ref>


===NMR solution structure of Myo10 anti-CC===
==See Also==
 
*[[Myosin 3D Structures|Myosin 3D Structures]]
 
== References ==
==About this Structure==
<references/>
[[2lw9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW9 OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lu, Q.]]
[[Category: Large Structures]]
[[Category: Ye, F.]]
[[Category: Lu Q]]
[[Category: Zhang, M.]]
[[Category: Ye F]]
[[Category: Motor protein]]
[[Category: Zhang M]]
[[Category: Myo10 anti-cc]]