2lz1: Difference between revisions
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New page: '''Unreleased structure''' The entry 2lz1 is ON HOLD Authors: Eletsky, A., Pulavarti, S.V.S.R.K., Lee, D., Kohan, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T.,... |
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==Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O== | |||
<StructureSection load='2lz1' size='340' side='right'caption='[[2lz1]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2lz1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LZ1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lz1 OCA], [https://pdbe.org/2lz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lz1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NF2L2_HUMAN NF2L2_HUMAN] Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.<ref>PMID:11035812</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Acton TB]] | |||
[[Category: Eletsky A]] | |||
[[Category: Everett JK]] | |||
[[Category: Janjua H]] | |||
[[Category: Kohan E]] | |||
[[Category: Lee D]] | |||
[[Category: Montelione GT]] | |||
[[Category: Pulavarti SVSRK]] | |||
[[Category: Szyperski T]] | |||
[[Category: Xiao R]] | |||
Latest revision as of 05:55, 15 May 2024
Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O
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