4hd0: Difference between revisions

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'''Unreleased structure'''


The entry 4hd0 is ON HOLD
==Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair==
 
<StructureSection load='4hd0' size='340' side='right'caption='[[4hd0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
Authors: Limbo, O., Moiani, D., Kertokalio, A., Wyman, C., Tainer, J.A., Russell, P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4hd0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HD0 FirstGlance]. <br>
Description: Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hd0 OCA], [https://pdbe.org/4hd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hd0 RCSB], [https://www.ebi.ac.uk/pdbsum/4hd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hd0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MRE11_PYRFU MRE11_PYRFU] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus furiosus DSM 3638]]
[[Category: Kertokalio A]]
[[Category: Limbo O]]
[[Category: Moiani D]]
[[Category: Russell P]]
[[Category: Tainer JA]]
[[Category: Wyman C]]
Retrieved from "https://proteopedia.org/4hd0"