4gta: Difference between revisions

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[[Image:4gta.jpg|left|200px]]


{{STRUCTURE_4gta| PDB=4gta | SCENE= }}  
==T. Maritima FDTS with FAD, dUMP, and Folinic Acid==
<StructureSection load='4gta' size='340' side='right'caption='[[4gta]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GTA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FFO:N-[4-({[(6S)-2-AMINO-5-FORMYL-4-OXO-3,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC+ACID'>FFO</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gta OCA], [https://pdbe.org/4gta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gta RCSB], [https://www.ebi.ac.uk/pdbsum/4gta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gta ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.


===T. Maritima FDTS with FAD, dUMP, and Folinic Acid===
==See Also==
 
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
{{ABSTRACT_PUBMED_23019356}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[4gta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GTA OCA].
[[Category: Thermotoga maritima MSB8]]
[[Category: Thermotoga maritima msb8]]
[[Category: Kohen A]]
[[Category: Kohen, A.]]
[[Category: Lesley SA]]
[[Category: Lesley, S A.]]
[[Category: Mathews II]]
[[Category: Mathews, I I.]]
[[Category: Flavin-dependent thymidylate synthase]]
[[Category: Folinic acid]]
[[Category: Tm0449]]
[[Category: Transferase]]

Latest revision as of 15:55, 14 March 2024

T. Maritima FDTS with FAD, dUMP, and Folinic Acid

4gta, resolution 1.50Å

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