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[[Image:1eic.png|left|200px]]


{{STRUCTURE_1eic|  PDB=1eic  |  SCENE=  }}
==CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A==
 
<StructureSection load='1eic' size='340' side='right'caption='[[1eic]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
===CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1eic]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EIC FirstGlance]. <br>
{{ABSTRACT_PUBMED_11742124}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eic OCA], [https://pdbe.org/1eic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eic RCSB], [https://www.ebi.ac.uk/pdbsum/1eic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eic ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1eic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EIC OCA].  
== Function ==
[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/1eic_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eic ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:011742124</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Pancreatic ribonuclease]]
[[Category: Large Structures]]
[[Category: Chatani, E.]]
[[Category: Chatani E]]
[[Category: Hayashi, R.]]
[[Category: Hayashi R]]
[[Category: Moriyama, H.]]
[[Category: Moriyama H]]
[[Category: Ueki, T.]]
[[Category: Ueki T]]
[[Category: Bovine pancrea]]
[[Category: Hydrolase]]
[[Category: Ribonuclease]]
[[Category: Rnase some]]
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