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[[Image:3siv.png|left|200px]]


{{STRUCTURE_3siv|  PDB=3siv  |  SCENE=  }}
==Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form==
 
<StructureSection load='3siv' size='340' side='right'caption='[[3siv]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
===Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3siv]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SIV FirstGlance]. <br>
{{ABSTRACT_PUBMED_21784869}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.304&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3siv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3siv OCA], [https://pdbe.org/3siv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3siv RCSB], [https://www.ebi.ac.uk/pdbsum/3siv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3siv ProSAT]</span></td></tr>
==About this Structure==
</table>
[[3siv]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SIV OCA].  
== Function ==
[https://www.uniprot.org/uniprot/NH2L1_HUMAN NH2L1_HUMAN] Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.<ref>PMID:10545122</ref> <ref>PMID:17412961</ref>


==See Also==
==See Also==
*[[Nucleoprotein|Nucleoprotein]]
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
==Reference==
== References ==
<ref group="xtra">PMID:021784869</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ghalei, H.]]
[[Category: Large Structures]]
[[Category: Liu, S.]]
[[Category: Ghalei H]]
[[Category: Luhrmann, R.]]
[[Category: Liu S]]
[[Category: Wahl, M C.]]
[[Category: Luhrmann R]]
[[Category: Major and minor spliceosome]]
[[Category: Wahl MC]]
[[Category: Nucleus]]
[[Category: Pre-mrna splicing]]
[[Category: Rna-binding protein]]
[[Category: Rna-protein complex]]
[[Category: Splicing-rna complex]]
[[Category: U4 snrna]]
[[Category: U4 snrnp and u4atac snrnp]]

Latest revision as of 12:58, 14 March 2024

Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form

3siv, resolution 3.30Å

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