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[[Image:3sq4.png|left|200px]]


{{STRUCTURE_3sq4|  PDB=3sq4  |  SCENE=  }}
==RB69 DNA Polymerase Ternary Complex with dTTP Opposite 2AP (GC rich sequence)==
 
<StructureSection load='3sq4' size='340' side='right'caption='[[3sq4]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
===RB69 DNA Polymerase Ternary Complex with dTTP Opposite 2AP (GC rich sequence)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3sq4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SQ4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_22023103}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DA:2,3-DIDEOXYADENOSINE-5-MONOPHOSPHATE'>2DA</scene>, <scene name='pdbligand=2PR:2-AMINO-9-[2-DEOXYRIBOFURANOSYL]-9H-PURINE-5-MONOPHOSPHATE'>2PR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sq4 OCA], [https://pdbe.org/3sq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sq4 RCSB], [https://www.ebi.ac.uk/pdbsum/3sq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sq4 ProSAT]</span></td></tr>
[[3sq4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQ4 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022023103</ref><references group="xtra"/>
[[Category: Escherichia phage RB69]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Enterobacteria phage rb69]]
[[Category: Konigsberg WH]]
[[Category: Konigsberg, W H.]]
[[Category: Wang J]]
[[Category: Wang, J.]]
[[Category: Xia S]]
[[Category: Xia, S.]]
[[Category: 2-aminopurine]]
[[Category: Gc rich]]
[[Category: Transferase-dna complex]]

Latest revision as of 09:54, 1 March 2024

RB69 DNA Polymerase Ternary Complex with dTTP Opposite 2AP (GC rich sequence)

3sq4, resolution 2.23Å

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