3m13: Difference between revisions
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==Crystal Structure of the Lys265Arg PEG-crystallized mutant of monomeric sarcosine oxidase== | |||
<StructureSection load='3m13' size='340' side='right'caption='[[3m13]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3m13]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._B-0618 Bacillus sp. B-0618]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M13 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m13 OCA], [https://pdbe.org/3m13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m13 RCSB], [https://www.ebi.ac.uk/pdbsum/3m13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m13 ProSAT]</span></td></tr> | ||
[[3m13]] is a 4 chain structure with sequence from [ | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MSOX_BACB0 MSOX_BACB0] Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L-alanine.[HAMAP-Rule:MF_00516] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/3m13_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m13 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Sarcosine oxidase|Sarcosine oxidase]] | *[[Sarcosine oxidase|Sarcosine oxidase]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus sp. B-0618]] | |||
[[Category: Bacillus sp.]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Chen Z-W]] | ||
[[Category: Chen | [[Category: Jorns MS]] | ||
[[Category: Jorns | [[Category: Mathews FS]] | ||
[[Category: Mathews | |||
Latest revision as of 10:23, 21 February 2024
Crystal Structure of the Lys265Arg PEG-crystallized mutant of monomeric sarcosine oxidase
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