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[[Image:1nlf.png|left|200px]]


{{STRUCTURE_1nlf|  PDB=1nlf  |  SCENE=  }}
==Crystal Structure of DNA Helicase RepA in complex with sulfate at 1.95 A resolution==
 
<StructureSection load='1nlf' size='340' side='right'caption='[[1nlf]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
===Crystal Structure of DNA Helicase RepA in complex with sulfate at 1.95 A resolution===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1nlf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NLF FirstGlance]. <br>
{{ABSTRACT_PUBMED_12777796}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nlf OCA], [https://pdbe.org/1nlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nlf RCSB], [https://www.ebi.ac.uk/pdbsum/1nlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nlf ProSAT]</span></td></tr>
[[1nlf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NLF OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/REPJ_ECOLX REPJ_ECOLX] This protein is involved in regulating the plasmid copy-number. Increasing the level of this protein results in a higher plasmid copy-number.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nl/1nlf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nlf ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Helicase|Helicase]]
*[[Helicase 3D structures|Helicase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:012777796</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Bottcher, C.]]
[[Category: Large Structures]]
[[Category: Ludwig, K.]]
[[Category: Bottcher C]]
[[Category: Saenger, W.]]
[[Category: Ludwig K]]
[[Category: Schroeder, W.]]
[[Category: Saenger W]]
[[Category: Strater, N.]]
[[Category: Schroeder W]]
[[Category: Xu, H.]]
[[Category: Strater N]]
[[Category: Replication]]
[[Category: Xu H]]
[[Category: Replicative dna helicase structural change]]