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[[Image:2ywc.png|left|200px]]


{{STRUCTURE_2ywc|  PDB=2ywc  |  SCENE=  }}
==Crystal structure of GMP synthetase from Thermus thermophilus in complex with XMP==
 
<StructureSection load='2ywc' size='340' side='right'caption='[[2ywc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal structure of GMP synthetase from Thermus thermophilus in complex with XMP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ywc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YWC FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>
[[2ywc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWC OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ywc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywc OCA], [https://pdbe.org/2ywc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ywc RCSB], [https://www.ebi.ac.uk/pdbsum/2ywc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ywc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ywc TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GUAA_THET8 GUAA_THET8] Catalyzes the synthesis of GMP from XMP (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yw/2ywc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ywc ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[GMP synthase|GMP synthase]]
*[[GMP synthase|GMP synthase]]
[[Category: Thermus thermophilus]]
__TOC__
[[Category: Baba, S.]]
</StructureSection>
[[Category: Kanagawa, M.]]
[[Category: Large Structures]]
[[Category: Kawai, G.]]
[[Category: Thermus thermophilus HB8]]
[[Category: Kuramitsu, S.]]
[[Category: Baba S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Kanagawa M]]
[[Category: Sampei, G.]]
[[Category: Kawai G]]
[[Category: Yokoyama, S.]]
[[Category: Kuramitsu S]]
[[Category: Atp binding]]
[[Category: Sampei G]]
[[Category: Gmp synthetase]]
[[Category: Yokoyama S]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Purine nucleotide biosynthetic pathway]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Xmp binding]]
Retrieved from "https://proteopedia.org/2ywc"