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[[Image:2ioq.png|left|200px]]


{{STRUCTURE_2ioq|  PDB=2ioq  |  SCENE=  }}
==Crystal Structure of full-length HTPG, the Escherichia coli HSP90==
 
<StructureSection load='2ioq' size='340' side='right'caption='[[2ioq]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
===Crystal Structure of full-length HTPG, the Escherichia coli HSP90===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ioq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The December 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Hsp90''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_12 10.2210/rcsb_pdb/mom_2008_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IOQ FirstGlance]. <br>
{{ABSTRACT_PUBMED_17055434}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ioq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ioq OCA], [https://pdbe.org/2ioq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ioq RCSB], [https://www.ebi.ac.uk/pdbsum/2ioq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ioq ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2ioq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The December 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Hsp90''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_12 10.2210/rcsb_pdb/mom_2008_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOQ OCA].  
== Function ==
[https://www.uniprot.org/uniprot/HTPG_ECOLI HTPG_ECOLI] Molecular chaperone. Has ATPase activity.[HAMAP-Rule:MF_00505]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/2ioq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ioq ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Heat Shock Proteins|Heat Shock Proteins]]
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:017055434</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Hsp90]]
[[Category: Hsp90]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Agard, D A.]]
[[Category: Agard DA]]
[[Category: Harris, S F.]]
[[Category: Harris SF]]
[[Category: Shiau, A K.]]
[[Category: Shiau AK]]
[[Category: Chaperone]]
[[Category: Heat shock protein]]
[[Category: Hsp90]]