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[[Image:1f1h.png|left|200px]]


{{STRUCTURE_1f1h|  PDB=1f1h  |  SCENE=  }}
==CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS==
 
<StructureSection load='1f1h' size='340' side='right'caption='[[1f1h]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
===CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1f1h]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F1H FirstGlance]. <br>
{{ABSTRACT_PUBMED_11329256}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.67&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f1h OCA], [https://pdbe.org/1f1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f1h RCSB], [https://www.ebi.ac.uk/pdbsum/1f1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f1h ProSAT]</span></td></tr>
[[1f1h]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1H OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLN1B_SALTY GLN1B_SALTY] Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.<ref>PMID:7727369</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f1/1f1h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f1h ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Glutamine Synthase|Glutamine Synthase]]
*[[Glutamine synthetase 3D structures|Glutamine synthetase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:011329256</ref><references group="xtra"/>
__TOC__
[[Category: Glutamate--ammonia ligase]]
</StructureSection>
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[[Category: Large Structures]]
[[Category: Eisenberg, D.]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Gill, H S.]]
[[Category: Eisenberg D]]
[[Category: Glutamine synthetase]]
[[Category: Gill HS]]
[[Category: Ligase]]
[[Category: Thallium ion]]

Latest revision as of 07:09, 7 February 2024

CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS

1f1h, resolution 2.67Å

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