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[[Image:1bsq.png|left|200px]]


{{STRUCTURE_1bsq|  PDB=1bsq  |  SCENE=  }}
==STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF POINT MUTATIONS OF VARIANTS A AND B OF BOVINE BETA-LACTOGLOBULIN==
 
<StructureSection load='1bsq' size='340' side='right'caption='[[1bsq]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
===STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF POINT MUTATIONS OF VARIANTS A AND B OF BOVINE BETA-LACTOGLOBULIN===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1bsq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BSQ FirstGlance]. <br>
{{ABSTRACT_PUBMED_10210185}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bsq OCA], [https://pdbe.org/1bsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bsq RCSB], [https://www.ebi.ac.uk/pdbsum/1bsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bsq ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1bsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSQ OCA].  
== Function ==
[https://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/1bsq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bsq ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Beta-lactoglobulin|Beta-lactoglobulin]]
*[[Beta-lactoglobulin 3D structures|Beta-lactoglobulin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010210185</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Baker, E N.]]
[[Category: Large Structures]]
[[Category: Bewley, M C.]]
[[Category: Baker EN]]
[[Category: Creamer, L K.]]
[[Category: Bewley MC]]
[[Category: Jameson, G B.]]
[[Category: Creamer LK]]
[[Category: Qin, B Y.]]
[[Category: Jameson GB]]
[[Category: Bovine beta-lactoglobulin]]
[[Category: Qin BY]]
[[Category: Genetic variant]]
[[Category: Hormone-growth factor complex]]
[[Category: Hydrophobic]]
[[Category: Point mutation]]
Retrieved from "https://proteopedia.org/1bsq"