2bo9: Difference between revisions

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[[Image:2bo9.png|left|200px]]


{{STRUCTURE_2bo9|  PDB=2bo9  |  SCENE= }}
==Human carboxypeptidase A4 in complex with human latexin.==
 
<StructureSection load='2bo9' size='340' side='right'caption='[[2bo9]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
===HUMAN CARBOXYPEPTIDASE A4 IN COMPLEX WITH HUMAN LATEXIN.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2bo9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2bk7 2bk7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BO9 FirstGlance]. <br>
{{ABSTRACT_PUBMED_15738388}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACN:ACETONE'>ACN</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bo9 OCA], [https://pdbe.org/2bo9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bo9 RCSB], [https://www.ebi.ac.uk/pdbsum/2bo9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bo9 ProSAT]</span></td></tr>
[[2bo9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2bk7 2bk7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BO9 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBPA4_HUMAN CBPA4_HUMAN] Metalloprotease that could be involved in the histone hyperacetylation pathway.<ref>PMID:10383164</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/2bo9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bo9 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Carboxypeptidase|Carboxypeptidase]]
*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:015738388</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Aviles, F X.]]
[[Category: Large Structures]]
[[Category: Bonet, R.]]
[[Category: Aviles FX]]
[[Category: Garcia-Castellanos, R.]]
[[Category: Bonet R]]
[[Category: Gomis-Rueth, F X.]]
[[Category: Garcia-Castellanos R]]
[[Category: Pallares, I.]]
[[Category: Gomis-Rueth FX]]
[[Category: Vendrell, J.]]
[[Category: Pallares I]]
[[Category: Ventura, S.]]
[[Category: Vendrell J]]
[[Category: Endogenous protein inhibitor]]
[[Category: Ventura S]]
[[Category: Hydrolase]]
[[Category: Latexin]]
[[Category: Metallocarboxypeptidase]]
[[Category: Metalloprotease carboxypeptidase]]
[[Category: X-ray crystal structure]]
Retrieved from "https://proteopedia.org/2bo9"