3r0w: Difference between revisions

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~~[[Image:3r0w.png|left|200px]]~~

~~{{STRUCTURE_3r0w| PDB=3r0w | SCENE= }}~~

==Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors.==

===Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors.===

== Structural highlights ==

<table><tr><td colspan='2'>[[3r0w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0W OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=3R0W FirstGlance].

~~{{ABSTRACT_PUBMED_22469467}}~~

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RSY:N-[(2R)-1-{[(2S,3S)-5-{[(2R)-1-{[(2S)-1-AMINO-4-METHYL-1-OXOPENTAN-2-YL]AMINO}-3-CHLORO-1-OXOPROPAN-2-YL]AMINO}-3-HYDROXY-5-OXO-1-PHENYLPENTAN-2-YL]AMINO}-3-METHYL-1-OXOBUTAN-2-YL]PYRIDINE-2-CARBOXAMIDE'>RSY</scene></td></tr>

==~~About this Structure~~==

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=3r0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r0w OCA], [https://pdbe.org/3r0w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r0w RCSB], [https://www.ebi.ac.uk/pdbsum/3r0w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r0w ProSAT]</td></tr>

[[3r0w]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0W OCA].

</table>

== Function ==

[https://www.uniprot.org/uniprot/Q000H7_9HIV1 Q000H7_9HIV1]

==See Also==

*[[~~Virus~~ protease|~~Virus~~ protease]]

*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]

__TOC__

~~==Reference==~~

</StructureSection>

~~<ref group="xtra">PMID:022469467</ref>~~<~~references group="xtra"~~/>

[[Category: Human immunodeficiency virus 1]]

[[Category: Brunzelle, J.]]

[[Category: Large Structures]]

[[Category: Gupta, D.]]

[[Category: Brunzelle J]]

[[Category: Kovari~~, I A.~~]]

[[Category: Gupta D]]

[[Category: Kovari~~, L C.~~]]

[[Category: Kovari IA]]

[[Category: Liu, Z.]]

[[Category: Kovari LC]]

[[Category: Woster~~, P M.~~]]

[[Category: Liu Z]]

[[Category: Yedidi~~, R S.]]~~

[[Category: Woster PM]]

~~[[Category: Hydrolase-hydrolase inhibitor complex~~]]

[[Category: Yedidi RS]]

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@@ Line 1: / Line 1: @@
-[[Image:3r0w.png|left|200px]]
-{{STRUCTURE_3r0w|  PDB=3r0w  |  SCENE=  }}
+==Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors.==
+<StructureSection load='3r0w' size='340' side='right'caption='[[3r0w]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-===Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors.===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3r0w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R0W FirstGlance]. <br>
-{{ABSTRACT_PUBMED_22469467}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RSY:N-[(2R)-1-{[(2S,3S)-5-{[(2R)-1-{[(2S)-1-AMINO-4-METHYL-1-OXOPENTAN-2-YL]AMINO}-3-CHLORO-1-OXOPROPAN-2-YL]AMINO}-3-HYDROXY-5-OXO-1-PHENYLPENTAN-2-YL]AMINO}-3-METHYL-1-OXOBUTAN-2-YL]PYRIDINE-2-CARBOXAMIDE'>RSY</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r0w OCA], [https://pdbe.org/3r0w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r0w RCSB], [https://www.ebi.ac.uk/pdbsum/3r0w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r0w ProSAT]</span></td></tr>
-[[3r0w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0W OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q000H7_9HIV1 Q000H7_9HIV1]
 ==See Also==
-*[[Virus protease|Virus protease]]
+*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:022469467</ref><references group="xtra"/>
 [[Category: Human immunodeficiency virus 1]]
-[[Category: Brunzelle, J.]]
+[[Category: Large Structures]]
-[[Category: Gupta, D.]]
+[[Category: Brunzelle J]]
-[[Category: Kovari, I A.]]
+[[Category: Gupta D]]
-[[Category: Kovari, L C.]]
+[[Category: Kovari IA]]
-[[Category: Liu, Z.]]
+[[Category: Kovari LC]]
-[[Category: Woster, P M.]]
+[[Category: Liu Z]]
-[[Category: Yedidi, R S.]]
+[[Category: Woster PM]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Yedidi RS]]