1qb2: Difference between revisions

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[[Image:1qb2.png|left|200px]]


{{STRUCTURE_1qb2|  PDB=1qb2  |  SCENE=  }}
==CRYSTAL STRUCTURE OF THE CONSERVED SUBDOMAIN OF HUMAN PROTEIN SRP54M AT 2.1A RESOLUTION: EVIDENCE FOR THE MECHANISM OF SIGNAL PEPTIDE BINDING==
 
<StructureSection load='1qb2' size='340' side='right'caption='[[1qb2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===CRYSTAL STRUCTURE OF THE CONSERVED SUBDOMAIN OF HUMAN PROTEIN SRP54M AT 2.1A RESOLUTION: EVIDENCE FOR THE MECHANISM OF SIGNAL PEPTIDE BINDING===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1qb2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QB2 FirstGlance]. <br>
{{ABSTRACT_PUBMED_10497032}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qb2 OCA], [https://pdbe.org/1qb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qb2 RCSB], [https://www.ebi.ac.uk/pdbsum/1qb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qb2 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1qb2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QB2 OCA].  
== Function ==
[https://www.uniprot.org/uniprot/SRP54_HUMAN SRP54_HUMAN] Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qb/1qb2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qb2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Signal recognition particle protein|Signal recognition particle protein]]
*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010497032</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Black, S D.]]
[[Category: Large Structures]]
[[Category: Clemons, W M.]]
[[Category: Black SD]]
[[Category: Gowda, K.]]
[[Category: Clemons Jr WM]]
[[Category: Ramakrishnan, V.]]
[[Category: Gowda K]]
[[Category: Zwieb, C.]]
[[Category: Ramakrishnan V]]
[[Category: Alpha-helix]]
[[Category: Zwieb C]]
[[Category: Helix-turn-helix]]
[[Category: Signaling protein]]
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