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[[Image:1ltk.gif|left|200px]]<br /><applet load="1ltk" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1ltk, resolution 3.00&Aring;" />
'''CRYSTAL STRUCTURE OF PHOSPHOGLYCERATE KINASE FROM PLASMODIUM FALCIPARUM, IN THE OPEN CONFORMATION'''<br />


==About this Structure==
==CRYSTAL STRUCTURE OF PHOSPHOGLYCERATE KINASE FROM PLASMODIUM FALCIPARUM, IN THE OPEN CONFORMATION==
1LTK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=AMP:'>AMP</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphoglycerate_kinase Phosphoglycerate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.3 2.7.2.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LTK OCA].  
<StructureSection load='1ltk' size='340' side='right'caption='[[1ltk]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
[[Category: Phosphoglycerate kinase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1ltk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LTK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ltk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ltk OCA], [https://pdbe.org/1ltk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ltk RCSB], [https://www.ebi.ac.uk/pdbsum/1ltk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ltk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PGK_PLAF7 PGK_PLAF7]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lt/1ltk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ltk ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Phosphoglycerate kinase 3D structures|Phosphoglycerate kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Single protein]]
[[Category: Chattopadhyay D]]
[[Category: Chattopadhyay, D.]]
[[Category: Pal B]]
[[Category: Pal, B.]]
[[Category: Smith CD]]
[[Category: Smith, C D.]]
[[Category: AMP]]
[[Category: GOL]]
[[Category: SO4]]
[[Category: adp complex]]
[[Category: glycerol]]
[[Category: glycolysis]]
[[Category: open conformation]]
[[Category: pgk]]
[[Category: phosphoglycerate kinase]]
[[Category: selenomethionine]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:48:17 2008''

Latest revision as of 06:59, 30 October 2024

CRYSTAL STRUCTURE OF PHOSPHOGLYCERATE KINASE FROM PLASMODIUM FALCIPARUM, IN THE OPEN CONFORMATION

1ltk, resolution 3.00Å

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