3v6j: Difference between revisions

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[[Image:3v6j.png|left|200px]]


{{STRUCTURE_3v6j|  PDB=3v6j  |  SCENE=  }}
==Replication of N2,3-Ethenoguanine by DNA Polymerases==
 
<StructureSection load='3v6j' size='340' side='right'caption='[[3v6j]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
===Replication of N2,3-Ethenoguanine by DNA Polymerases===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3v6j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V6J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V6J FirstGlance]. <br>
{{ABSTRACT_PUBMED_22488769}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCP:2-DEOXYCYTIDINE-5-TRIPHOSPHATE'>DCP</scene>, <scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=EFG:1-(2-DEOXY-2-FLUORO-5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-1H-IMIDAZO[2,1-B]PURIN-4(5H)-ONE'>EFG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v6j OCA], [https://pdbe.org/3v6j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v6j RCSB], [https://www.ebi.ac.uk/pdbsum/3v6j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v6j ProSAT]</span></td></tr>
[[3v6j]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V6J OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022488769</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Saccharolobus solfataricus P2]]
[[Category: Sulfolobus solfataricus p2]]
[[Category: Zhao L]]
[[Category: Zhao, L.]]
[[Category: 2'-fluoro arabinose]]
[[Category: 3-ethenoguanine]]
[[Category: Dna adduct]]
[[Category: Dna lesion]]
[[Category: Dna polymerase]]
[[Category: Dna replication]]
[[Category: Dpo4]]
[[Category: Ethenoguanine]]
[[Category: Lesion bypass]]
[[Category: N2]]
[[Category: Sulfolobus solfataricus dna polymerase iv]]
[[Category: Transferase-dna complex]]
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