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[[Image:1ubx.png|left|200px]]


{{STRUCTURE_1ubx|  PDB=1ubx  |  SCENE=  }}
==STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE==
 
<StructureSection load='1ubx' size='340' side='right'caption='[[1ubx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1ubx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UBX FirstGlance]. <br>
{{ABSTRACT_PUBMED_8986756}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ubx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ubx OCA], [https://pdbe.org/1ubx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ubx RCSB], [https://www.ebi.ac.uk/pdbsum/1ubx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ubx ProSAT]</span></td></tr>
[[1ubx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UBX OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/FPPS_CHICK FPPS_CHICK] Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ub/1ubx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ubx ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]
*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008986756</ref><references group="xtra"/>
[[Category: Dimethylallyltranstransferase]]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Poulter, C D.]]
[[Category: Large Structures]]
[[Category: Proteau, P.]]
[[Category: Poulter CD]]
[[Category: Sacchettini, J C.]]
[[Category: Proteau P]]
[[Category: Tarshis, L C.]]
[[Category: Sacchettini JC]]
[[Category: Cholesterol biosynthesis]]
[[Category: Tarshis LC]]
[[Category: Isoprene biosynthesis]]
[[Category: Transferase]]