3hnc: Difference between revisions

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[[Image:3hnc.png|left|200px]]


{{STRUCTURE_3hnc|  PDB=3hnc  |  SCENE=  }}
==Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP==
 
<StructureSection load='3hnc' size='340' side='right'caption='[[3hnc]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
===Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3hnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HNC FirstGlance]. <br>
{{ABSTRACT_PUBMED_21336276}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hnc OCA], [https://pdbe.org/3hnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hnc RCSB], [https://www.ebi.ac.uk/pdbsum/3hnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hnc ProSAT]</span></td></tr>
[[3hnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HNC OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RIR1_HUMAN RIR1_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


==See Also==
==See Also==
*[[Ribonucleotide reductase|Ribonucleotide reductase]]
*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021336276</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Large Structures]]
[[Category: Dealwis, C G.]]
[[Category: Dealwis CG]]
[[Category: Fairman, J W.]]
[[Category: Fairman JW]]
[[Category: Wijerathna, S R.]]
[[Category: Wijerathna SR]]
[[Category: Xu, H.]]
[[Category: Xu H]]
[[Category: Allosteric enzyme]]
[[Category: Atp-binding]]
[[Category: Dna replication]]
[[Category: Nucleotide-binding]]
[[Category: Oxidoreductase]]
[[Category: Ribonucleotide reductase]]
Retrieved from "https://proteopedia.org/3hnc"