1i08: Difference between revisions

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[[Image:1i08.png|left|200px]]


{{STRUCTURE_1i08|  PDB=1i08  |  SCENE=  }}
==CRYSTAL STRUCTURE ANALYSIS OF THE H30A MUTANT OF MANGANESE SUPEROXIDE DISMUTASE FROM E. COLI==
 
<StructureSection load='1i08' size='340' side='right'caption='[[1i08]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===CRYSTAL STRUCTURE ANALYSIS OF THE H30A MUTANT OF MANGANESE SUPEROXIDE DISMUTASE FROM E. COLI===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1i08]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I08 FirstGlance]. <br>
{{ABSTRACT_PUBMED_11294629}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i08 OCA], [https://pdbe.org/1i08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i08 RCSB], [https://www.ebi.ac.uk/pdbsum/1i08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i08 ProSAT]</span></td></tr>
[[1i08]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I08 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i0/1i08_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i08 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Superoxide Dismutase|Superoxide Dismutase]]
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:011294629</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Superoxide dismutase]]
[[Category: Large Structures]]
[[Category: Baker, E N.]]
[[Category: Baker EN]]
[[Category: Edwards, R A.]]
[[Category: Edwards RA]]
[[Category: Jameson, G B.]]
[[Category: Jameson GB]]
[[Category: Whittaker, J W.]]
[[Category: Whittaker JW]]
[[Category: Whittaker, M M.]]
[[Category: Whittaker MM]]
[[Category: H30a]]
[[Category: Hydrogen bond]]
[[Category: Manganese superoxide dismutase]]
[[Category: Mutant]]
[[Category: Oxidoreductase]]
[[Category: Reactivity]]

Latest revision as of 07:31, 7 February 2024

CRYSTAL STRUCTURE ANALYSIS OF THE H30A MUTANT OF MANGANESE SUPEROXIDE DISMUTASE FROM E. COLI

1i08, resolution 2.20Å

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